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Article

Genotype to phenotype: analyzing the effects of inherited mutations in colorectal cancer families.

Mutation research - 10 Nov 2010

Heinen Christopher D

Abstract excerpt

With improvements to DNA sequencing technologies, including the advent of massively parallel sequencing to perform "deep sequencing" of tissue samples, the ability to determine all of the nucleotide variations in a tumor becomes a possibility. This information will allow us to more fully understand the heterogeneity within each tumor, as well as to identify novel genes involved in cancer development. However, the...

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Share to Adenomatous Polyposis Coli
Share to Colorectal Neoplasms
Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genes, APC

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Source

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Identifiers

PMID: 19766128
DOI: 10.1016/j.mrfmmm.2009.09.004
PMCID: PMC2891646

Genes

APC
FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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