Article

Expanding the Genetic Spectrum of Hereditary Polyposis Syndromes: A Multicenter Study from Argentina

2026-04-16

Abstract excerpt

<title>Abstract</title> <p> Hereditary polyposis syndromes (HPS) predispose to colorectal cancer, yet their genetic landscape in Argentina remains underrepresented. We analyzed 177 probands from 163 unrelated families recruited through three Argentine reference centers. Genetic testing included <italic>APC</italic> and <italic>MUTYH</italic> analysis by Sanger sequencing and MLPA, complemented by multigene p...

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Literature Corpus work: 14e5a327-404b-59c1-bb9d-725063b6f89a
DOI: 10.21203/rs.3.rs-8163864/v1

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