Article
Genetic syndromes and genetic tests in colorectal cancer.
Seminars in gastrointestinal disease - 1 Oct 2000
Calland J F, Adams R B, DePrince K, Foley E F, Powell S M
Abstract excerpt
Our understanding of the biology of colon cancer has matured to the point that it is a useful general paradigm for understanding solid tumor development. Recent advances provide insight into the genetic alterations underlying the development of colon cancer. These insights provide unique opportunities for genetic testing in predisposed, asymptomatic patients that can direct screening efforts and their clinical...
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