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Article

Fine mapping of a linkage region on chromosome 17p13 reveals that GABARAP and DLG4 are associated with vulnerability to nicotine dependence in European-Americans.

Human molecular genetics - 15 Jan 2007

Lou Xiang-Yang, Ma Jennie Z, Sun Dongxiao, Payne Thomas J, Li Ming D

Abstract excerpt

A two-stage association study was conducted targeting a genomic region on chromosome 17p13 that we reported likely to harbor susceptibility gene(s) for nicotine dependence (ND). Participants were 2037 subjects from 602 nuclear families of either African-American (AA) or European-American (EA) origin from our Mid-South Tobacco Family (MSTF) cohort. We first examined 10 single nucleotide polymorphisms (SNPs) in six...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 17

Share to Disks Large Homolog 4 Protein

Share to Intracellular Signaling Peptides and Proteins

Share to Microtubule-Associated Proteins

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Source

Identifiers

PMID: 17164261
DOI: 10.1093/hmg/ddl450

Genes

DLG4
GABARAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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