Article
Influences of matrix metalloproteinase-3 gene variation on extent of coronary atherosclerosis and risk of myocardial infarction.
Journal of the American College of Cardiology - 18 Jun 2003
Beyzade Seyyare, Zhang Shaoli, Wong Yuk-ki, Day Ian N M, Eriksson Per, Ye Shu
Abstract excerpt
OBJECTIVES: The aim of this study was to assess matrix metalloproteinase-3 (MMP3) gene variation in relation to the degree of coronary atherosclerosis and risk of myocardial infarction (MI) in patients with coronary artery disease. METHODS: In this study, we systematically screened the promoter and coding regions for sequence variants. All polymorphisms identified were analyzed in 1,240 individuals undergoing...
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