Article
Haplotype analysis of the matrix metalloproteinase 3 gene and myocardial infarction in a Chinese Han population. The Beijing atherosclerosis study.
Thrombosis and haemostasis - 1 Oct 2004
Zhou Xiaoyang, Huang Jianfeng, Chen Jianhong, Su Shaoyong, Chen Runsheng, Gu Dongfeng
Abstract excerpt
Matrix metalloproteinase (MMP) 3 plays an important role in the pathogenesis of myocardial infarction (MI). Up to now, there has been conflicting data regarding the possible contribution of the MMP3 -1612 5A/6A promoter polymorphism to MI. In this study, we have investigated the possible association of three polymorphisms (-1612 5A/6A, -376C/G, Glu45Lys) in the MMP3 gene with MI in a Chinese Han population. The...
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