Article
A genetic algorithm based method for stringent haplotyping of family data.
BMC genetics - 17 Sept 2009
Besnier Francois, Carlborg Orjan
Abstract excerpt
BACKGROUND: The linkage phase, or haplotype, is an extra level of information that in addition to genotype and pedigree can be useful for reconstructing the inheritance pattern of the alleles in a pedigree, and computing for example Identity By Descent probabilities. If a haplotype is provided, t...
Topics
- Algorithms
- Alleles
- Computational Biology
- Computer Simulation
- Haplotypes
- Humans
- Models, Genetic
- Pedigree
- Sequence Analysis, DNA