Article
A genetic algorithm based method for stringent haplotyping of family data.
BMC genetics - 17 Sept 2009
Besnier Francois, Carlborg Orjan
Abstract excerpt
BACKGROUND: The linkage phase, or haplotype, is an extra level of information that in addition to genotype and pedigree can be useful for reconstructing the inheritance pattern of the alleles in a pedigree, and computing for example Identity By Descent probabilities. If a haplotype is provided, the precision of estimated IBD probabilities increases, as long as the haplotype is estimated without errors. It is...
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