Haplotyping and estimation of haplotype frequencies for closely linked biallelic multilocus genetic phenotypes including nuclear family information.

doi:10.1002/humu.26

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Article

Haplotyping and estimation of haplotype frequencies for closely linked biallelic multilocus genetic phenotypes including nuclear family information.

Human mutation - 1 Apr 2001

Rohde K, Fuerst R

Abstract excerpt

With the discovery of single nucleotide polymorphisms (SNP) along the genome, genotyping of large samples of biallelic multilocus genetic phenotypes for (fine) mapping of disease genes or for population studies has become standard practice. A genetic trait, however, is mainly caused by an underly...

Topics

Algorithms
Alleles
Chromosome Mapping
Computer Simulation
Female
Gene Frequency
Genetic Linkage
Haplotypes
Heterozygote
Humans
Likelihood Functions
Male
Nuclear Family
Phenotype
Software

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