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Article

Hepatocyte nuclear factor 1 coordinates multiple processes in a model of intestinal epithelial cell function.

Biochimica et biophysica acta - 1 Apr 2016

Yang Rui, Kerschner Jenny L, Harris Ann

Abstract excerpt

Mutations in hepatocyte nuclear factor 1 transcription factors (HNF1α/β) are associated with diabetes. These factors are well studied in the liver, pancreas and kidney, where they direct tissue-specific gene regulation. However, they also have an important role in the biology of many other tissues, including the intestine. We investigated the transcriptional network governed by HNF1 in an intestinal epithelial...

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Source

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Identifiers

PMID: 26855178
DOI: 10.1016/j.bbagrm.2016.02.005
PMCID: PMC4818657

Genes

CDX2
FOXA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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