Article
Flow cytometric determination of the multidrug-resistant phenotype in acute leukemia.
Cytometry - 1 Sept 1994
Maslak P, Hegewisch-Becker S, Godfrey L, Andreeff M
Abstract excerpt
Expression of the multidrug-resistant (MDR) phenotype was investigated in acute leukemia using a monoclonal antibody (HYB-241) directed against a cell surface epitope of the 180 kd P-glycoprotein (gp180) by flow cytometric analysis of clinical samples. Samples from sixty-four patients were tested (37 with acute myelocytic leukemia, 20 with acute lymphocytic leukemia, and 7 with blastic chronic myelocytic...
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