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Article

FISH and SNP-A karyotyping in myelodysplastic syndromes: improving cytogenetic detection of del(5q), monosomy 7, del(7q), trisomy 8 and del(20q).

Leukemia research - 1 Apr 2010

Makishima Hideki, Rataul Manjot, Gondek Lukasz P, Huh Jungwon, Cook James R, Theil Karl S, Sekeres Mikkael A, Kuczkowski Elizabeth, O'Keefe Christine, Maciejewski Jaroslaw P

Abstract excerpt

Cytogenetic aberrations identified by metaphase cytogenetics (MC) have important diagnostic, prognostic and therapeutic roles in myelodysplastic syndromes (MDS). Fluorescence in situ hybridization (FISH) complements MC by the ability to evaluate large numbers of both interphase and metaphase nuclei. However, clinically practical FISH strategies are limited to detection of known lesions. Single nucleotide...

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Identifiers

PMID: 19758696
DOI: 10.1016/j.leukres.2009.08.023
PMCID: PMC2826525

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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