Article
Characterization of chromosome arm 20q abnormalities in myeloid malignancies using genome-wide single nucleotide polymorphism array analysis.
Genes, chromosomes & cancer - 1 Apr 2010
Huh Jungwon, Tiu Ramon V, Gondek Lukasz P, O'Keefe Christine L, Jasek Monika, Makishima Hideki, Jankowska Ania M, Jiang Ying, Verma Amit, Theil Karl S, McDevitt Michael A, Maciejewski Jaroslaw P
Abstract excerpt
Deletion of the long arm of chromosome 20 is a common abnormality associated with myeloid malignancies. We characterized abnormalities of chromosome 20 as defined by metaphase cytogenetics (MC) in patients with myeloid neoplasms to define commonly deleted regions (CDR) and commonly retained regions (CRR) using genome-wide, high resolution single nucleotide polymorphism array (SNP-A) analysis. We reviewed the MC...
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