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Article

The prognostic significance of single-nucleotide polymorphism array-based whole-genome analysis and uniparental disomy in myelodysplastic syndrome.

International journal of laboratory hematology - 1 Oct 2021

Ou Yang, Yang Yan, Yu Hongbin, Zhang Xin, Liu Min, Wu Yu

Abstract excerpt

INTRODUCTION: Myelodysplastic syndrome (MDS) is a group of heterogeneous hematological diseases characterized by ineffective hematopoiesis and dysplastic morphology. Single nucleotide polymorphism array (SNP-A)-based whole genome analysis has a much higher resolution for chromosomal alterations when compared with conventional cytogenetic tools. In the present study, we evaluated the diagnostic value and...

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Identifiers

PMID: 33650312
DOI: 10.1111/ijlh.13502
PMCID: PMC8518839

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