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Article

Tyrosine kinase 2 and interferon regulatory factor 5 polymorphisms are associated with discoid and subacute cutaneous lupus erythematosus.

Experimental dermatology - 1 Feb 2010

Järvinen Tiina M, Hellquist Anna, Koskenmies Sari, Einarsdottir Elisabet, Koskinen Lotta L E, Jeskanen Leila, Berglind Linda, Panelius Jaana, Hasan Taina, Ranki Annamari, Kere Juha, Saarialho-Kere Ulpu

Abstract excerpt

Lupus erythematosus (LE) is a heterogeneous disease ranging from skin-restricted manifestations to a progressive multisystem disease. The specific skin lesions include chronic cutaneous, subacute cutaneous and acute cutaneous LE. Both genetic and environmental factors are involved in the development of LE. However, reports on the genetic background of cutaneous lupus erythematosus (CLE) forms, namely discoid...

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Source

Identifiers

PMID: 19758313
DOI: 10.1111/j.1600-0625.2009.00982.x

Genes

TYK2
CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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