Article
Interleukin-10 gene polymorphisms are associated with the SLICC/ACR Damage Index in systemic lupus erythematosus.
Rheumatology (Oxford, England) - 1 Apr 2006
Sung Y-K, Park B L, Shin H D, Kim L H, Kim S-Y, Bae S-C
Abstract excerpt
OBJECTIVE: Overproduction of interleukin-10 (IL-10) is a pivotal feature in the pathophysiology of systemic lupus erythematosus (SLE). We examined the IL10 genotype of Korean patients with SLE and normal controls to determine whether associations exist between the pattern of inherited IL10 genes and SLE susceptibility or the SLICC/ACR Damage Index (SDI). METHODS: A total of 350 Korean SLE patients and 330 healthy...
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