Article
Analysis of the int-1, int-2, c-myc, and neu oncogenes in human breast carcinomas.
Cancer research - 15 Sept 1990
Meyers S L, O'Brien M T, Smith T, Dudley J P
Abstract excerpt
We have examined the DNA obtained from 100 primary breast carcinomas for oncogene markers which might have predictive value for poor prognosis. Ninety-six of the tumors were analyzed for the presence of restriction fragment length polymorphisms (RFLPs) previously identified in the int-2 gene. An 8.4-kilobase BamHI fragment and a 3.9-kilobase PstI fragment specific for the int-2 gene, in the absence of other...
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