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Article

Quantitative DNA fingerprinting may distinguish new primary breast cancer from disease recurrence.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 15 May 2004

Schlechter Benjamin L, Yang Qiong, Larson Pamela S, Golubeva Arina, Blanchard Rita A, de las Morenas Antonio, Rosenberg Carol L

Abstract excerpt

PURPOSE: Approximately 10% of women with breast cancer develop a second breast tumor, either a new primary or a recurrence. Differentiating between these entities using standard clinical and pathologic criteria remains challenging. Ambiguous cases arise, and misclassifications may occur. We investigated whether quantitative DNA fingerprinting, based on allele imbalance (AI) or loss of heterozygosity (LOH), could...

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Source

Identifiers

PMID: 15143075
DOI: 10.1200/JCO.2004.05.123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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