Article
Dynamic and differential regulation of proteins that coat lipid droplets in fatty liver dystrophic mice.
Journal of lipid research - 1 Mar 2010
Hall Angela M, Brunt Elizabeth M, Chen Zhouji, Viswakarma Navin, Reddy Janardan K, Wolins Nathan E, Finck Brian N
Abstract excerpt
Lipid droplet proteins (LDPs) coat the surface of triglyceride-rich lipid droplets and regulate their formation and lipolysis. We profiled hepatic LDP expression in fatty liver dystrophic (fld) mice, a unique model of neonatal hepatic steatosis that predictably resolves between postnatal day 14 (P14) and P17. Western blotting revealed that perilipin-2/ADRP and perilipin-5/OXPAT were markedly increased in...
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