Article
Variation in tryptophan hydroxylase-2 gene is not associated to male completed suicide in Estonian population.
Neuroscience letters - 3 Apr 2009
Must Anne, Tasa Gunnar, Lang Aavo, Vasar Eero, Kõks Sulev, Maron Eduard, Väli Marika
Abstract excerpt
Dysfunction of the central serotonergic system has been related to a spectrum of psychiatric disorders, including suicidal behavior. Tryptophan hydroxylase isoform 2 (TPH2) is the rate-limiting enzyme in the biosynthetic pathway of serotonin, being expressed in serotonergic neurons of raphe nucle...
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