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Article

Interactions among genetic variants from SREBP2 activating-related pathway on risk of coronary heart disease in Chinese Han population.

Atherosclerosis - 1 Feb 2010

Liu Xiaoli, Li Yun, Lu Xiangfeng, Wang Laiyuan, Zhao Qi, Yang Wei, Huang Jianfeng, Cao Jie, Li Hongfan, Gu Dongfeng

Abstract excerpt

Sterol regulatory element binding proteins (SREBPs), as a family of membrane-bound transcription factors, control the metabolism of cholesterol and fatty acids. We conducted a case-control study to investigate whether the common variants of genes from the SREBP2 activating-related pathway, involving SREBP2, SCAP, INSIG1 and INSIG2 genes, were associated with coronary heart disease (CHD) of Chinese Han population...

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Source

Identifiers

PMID: 19740467
DOI: 10.1016/j.atherosclerosis.2009.08.011

Genes

INSIG1
INSIG2
SCAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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