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Article

The combined effects of cardiovascular disease related SNPs on ischemic stroke.

Journal of the neurological sciences - 15 May 2018

Xu Ke, Liu Xin, Ott Jurg, Jiang Feng, Zhang Wei, Wang Lefeng, Zhao Jingbo, Wang Xingyu

Abstract excerpt

PURPOSE: Previous studies have revealed multiple common variants associated with known risk factors for cardiovascular disease (CVD). Ischemic stroke (IS) and CVD share several risk factors with each having substantial heritability. We aimed to generate a multi-locus genetic risk score (GRS) for IS based on CVD related SNPs to evaluate their combined effects on IS. METHODS: A total of 851 patients and 977...

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PMID: 29627009
DOI: 10.1016/j.jns.2018.03.013

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