Article
Pleiotropy and heterogeneity in the expression of atherogenic lipoproteins: the IRAS Family Study.
Human heredity - 1 Jan 2003
Hokanson John E, Langefeld Carl D, Mitchell Braxton D, Lange Leslie A, Goff David C, Haffner Steven M, Saad Mohammad F, Rotter Jerome I
Abstract excerpt
OBJECTIVE: Dyslipidemia is an important determinant of coronary disease. Phenotypic correlations between atherogenic lipids are well established, but the contribution of common genetic influences is less clear. METHODS: This study investigates the pair-wise genetic (rhog) and environmental (rhoe) correlations between apoB, LDL-C, HDL-C, and triglyceride (Tg) from Hispanic and African American families of the IRAS...
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