Article
Association of CTLA-4 gene promoter polymorphisms with systemic sclerosis in Iranian population.
Genes and immunity - 1 Jul 2006
Almasi S, Erfani N, Mojtahedi Z, Rajaee A, Ghaderi A
Abstract excerpt
In a recent study, we were unable to show any association between CTLA-4 exon-1 polymorphism and systemic sclerosis (SSc) in Iranian population. In order to further explore the role of this immune inhibitory gene in SSc development, in the present study, the polymorphisms in the CTLA-4 promoter region (-1,722 T/C, -1,661 A/G and -318 C/T) were investigated in 83 SSc patients and 166 healthy controls. All...
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