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Article

A myeloperoxidase promoter polymorphism is independently associated with mortality in patients with impaired left ventricular function.

Free radical biology & medicine - 1 Dec 2009

Rudolph Volker, Rudolph Tanja K, Kubala Lukas, Clauberg Navina, Maas Renke, Pekarova Michaela, Klinke Anna, Lau Denise, Szöcs Katalin, Meinertz Thomas, Böger Rainer H, Baldus Stephan

Abstract excerpt

Circulating levels of myeloperoxidase (MPO), a heme enzyme released upon activation of polymorphonuclear neutrophils, predict adverse outcome in patients with impaired left ventricular (LV) function. The MPO -463 G/A promoter polymorphism (rs 2333227) regulates MPO transcription, with the G allele being linked to increased protein expression. The aim of this study was to assess the prognostic information derived...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19735726
DOI: 10.1016/j.freeradbiomed.2009.09.001

Genes

MPO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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