Article
Association between myeloperoxidase polymorphisms and its plasma levels with severity of coronary artery disease.
Clinical biochemistry - 1 Jan 2010
Wainstein Rodrigo V, Wainstein Marco V, Ribeiro Jorge P, Dornelles Laura V, Tozzati Paula, Ashton-Prolla Patrícia, Ewald Ingrid P, Vietta Giovana, Polanczyk Carisi A
Abstract excerpt
OBJECTIVES: Myeloperoxidase (MPO) polymorphism -463 has been related to higher cardiovascular risk. This study was conducted to test whether the MPO promoter polymorphism -463A/G and MPO plasma levels are associated with coronary artery disease (CAD) severity. DESIGN AND METHODS: Patients submitted to elective coronariography were enrolled, CAD severity was assessed and blood samples collected to identify the MPO...
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