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Article

The molecular genetics of the bithorax complex of Drosophila: cis-regulation in the Abdominal-B domain.

The EMBO journal - 1 Dec 1990

Celniker S E, Sharma S, Keelan D J, Lewis E B

Abstract excerpt

In Drosophila the Abdominal-B (Abd-B) domain of the bithorax complex (BX-C) spans over 100 kb and is responsible for specifying the identities of adult abdominal segments five (A5) to nine (A9), inclusive, and correspondingly, neuromeres 10-14 of the embryonic central nervous system. The domain consists of a region coding for two proteins, ABD-BI (54 kd) and ABD-BII (36 kd) and cis-regulatory regions extending...

Topics

Abdomen
Animals
Chromosomes
Drosophila
Drosophila Proteins
Gene Expression Regulation
Head
Homeodomain Proteins
Homozygote
Insect Hormones
Male
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Regulatory Sequences, Nucleic Acid

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Identifiers

PMID: 2265608
DOI: 10.1002/j.1460-2075.1990.tb07876.x
PMCID: PMC552210

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2265608-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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The molecular genetics of the bithorax complex of Drosophila: cis-regulation in the Abdominal-B domain.PMID 2265608Read ↗

Control of the expression of the bithorax complex genes abdominal-A and abdominal-B by cis-regulatory regions in Drosophila embryos.Semantic proximity Read ↗

Molecular definition of the morphogenetic and regulatory functions and the cis-regulatory elements of the Drosophila Abd-B homeotic gene.Semantic proximity Read ↗

Genetic and molecular characterization of a novel iab-8 regulatory domain in the Abdominal-B gene of Drosophila melanogaster.Semantic proximity Read ↗

Genetic organization of Drosophila bithorax complex.Semantic proximity Read ↗

Expression and regulation of the abd-A gene of Drosophila.Semantic proximity Read ↗

Segmental determination in Drosophila central nervous system: analysis of the abdominal-A region of the bithorax complex.Semantic proximity Read ↗

Cis and trans interactions between the iab regulatory regions and abdominal-A and abdominal-B in Drosophila melanogaster.Semantic proximity Read ↗

The Fab-8 boundary defines the distal limit of the bithorax complex iab-7 domain and insulates iab-7 from initiation elements and a PRE in the adjacent iab-8 domain.Semantic proximity Read ↗

Molecular basis of transabdominal--a sexually dimorphic mutant of the bithorax complex of Drosophila.Semantic proximity Read ↗

A new homeotic mutation in the Drosophila bithorax complex removes a boundary separating two domains of regulation.Semantic proximity Read ↗

Transvection in the iab-5,6,7 region of the bithorax complex of Drosophila: homology independent interactions in trans.Semantic proximity Read ↗

Transvection in the Drosophila Abd-B domain: extensive upstream sequences are involved in anchoring distant cis-regulatory regions to the promoter.Semantic proximity Read ↗

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