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Article

Neuregulin-1, the fetal endothelium, and brain damage in preterm newborns.

Brain, behavior, and immunity - 1 Jul 2010

Hoffmann Insa, Bueter Wolfgang, Zscheppang Katja, Brinkhaus Maria-Jantje, Liese Andrea, Riemke Stefan, Dörk Thilo, Dammann Olaf, Dammann Christiane E L

Abstract excerpt

OBJECTIVE: To assess the potential role for Neuregulin-1 (NRG1) as a systemic endogenous protector in the setting of perinatal inflammatory brain damage. METHODS: We measured NRG1-protein and mRNA levels in human umbilical venous endothelial cells (HUVECs) of different gestational ages at various durations of exposure to lipopolysaccharide (LPS). In parallel, we genotyped the donor individuals for SNP8NRG221533,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19733651
DOI: 10.1016/j.bbi.2009.08.012
PMCID: PMC2885532

Genes

NRG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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