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Article

Apolipoprotein E Genotype in Very Preterm Neonates with Intrauterine Growth Restriction: An Analysis of the German Neonatal Network Cohort.

BioMed research international - 1 Jan 2017

Norda Stephen, Rausch Tanja K, Orlikowsky Thorsten, Hütten Matthias, Schulz Sören, Göpel Wolfgang, Pecks Ulrich

Abstract excerpt

Aim. Cord blood of intrauterine growth restricted (IUGR) neonates displays lipid changes towards atherosclerotic profiles. Apolipoprotein E (ApoE) and its isoforms (e2, e3, and e4) are involved in the regulation of lipid metabolism. Specifically, ApoE e4 has been associated with atherosclerotic diseases, while e2 has a favorable effect. We therefore hypothesized that ApoE e4 haplotype is frequently observed in...

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Identifiers

PMID: 28480219
DOI: 10.1155/2017/2837027
PMCID: PMC5396432

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