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Article

Genetic associations of relaxin: preterm birth and premature rupture of fetal membranes.

American journal of obstetrics and gynecology - 1 Sept 2013

Rocha Frederico G, Slavin Thomas P, Li Dongmei, Tiirikainen Maarit I, Bryant-Greenwood Gillian D

Abstract excerpt

OBJECTIVE: Relaxin H2 (RLN2) is a systemic hormone (sRLN) that is produced by the corpus luteum, whereas decidual RLN (dRLN) acts only locally. Elevated sRLN is associated with spontaneous preterm birth (sPTB) and elevated dRLN with preterm premature rupture of membranes (PPROM). Associations were sought between single nucleotide polymorphisms (SNPs) in the RLN2 promoter with levels of dRLN and sRLN in Filipino...

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Share to Immunohistochemistry
Share to Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Promoter Regions, Genetic

Source

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Identifiers

PMID: 23727041
DOI: 10.1016/j.ajog.2013.05.020
PMCID: PMC3758420

Genes

RLN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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