Article
Genetic Variation, Magnesium Sulfate Exposure, and Adverse Neurodevelopmental Outcomes Following Preterm Birth.
American journal of perinatology - 1 Aug 2018
Clark Erin A S, Weiner Steven J, Rouse Dwight J, Mercer Brian M, Reddy Uma M, Iams Jay D, Wapner Ronald J, Sorokin Yoram, Malone Fergal D, O'Sullivan Mary J, Peaceman Alan M, Hankins Gary D V, Dudley Donald J, Caritis Steve N
Abstract excerpt
OBJECTIVE: To evaluate the association of magnesium sulfate (MgSO4) exposure and candidate gene polymorphisms with adverse neurodevelopmental outcomes following preterm birth. STUDY DESIGN: We performed a nested case-control analysis of a randomized trial of maternal MgSO4 before anticipated preterm birth for the prevention of cerebral palsy (CP). Cases were children who died within 1 year of life or were...
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