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Article

Associations of a PTPN11 G/A polymorphism at intron 3 with Helicobactor pylori seropositivity, gastric atrophy and gastric cancer in Japanese.

BMC gastroenterology - 9 Jul 2009

Hishida Asahi, Matsuo Keitaro, Goto Yasuyuki, Naito Mariko, Wakai Kenji, Tajima Kazuo, Hamajima Nobuyuki

Abstract excerpt

BACKGROUND: Previous studies have revealed the significance of Helicobacter pylori (H. pylori) infection as a risk factor of gastric cancer. Cytotoxin-associated gene A (cagA) positivity has been demonstrated to determine the clinical outcome of H. pylori infection in the presence of SHP-2 (src homology 2 domain-containing protein tyrosine phosphatase-2). This study aimed to examine the formerly reported...

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Source

Open in PubMed Open full text

Identifiers

PMID: 19589142
DOI: 10.1186/1471-230X-9-51
PMCID: PMC2715419

Genes

PTPN11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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