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Article

LIN54 is an essential core subunit of the DREAM/LINC complex that binds to the cdc2 promoter in a sequence‐specific manner

2 Sept 2009

Abstract excerpt

Recently, the conserved human LINC/DREAM complex has been described as an important regulator of cell cycle genes. LINC consists of a core module that dynamically associates with E2F transcription factors, p130 and the B‐MYB transcription factor in a cell cycle‐dependent manner. In this study, we analyzed the evolutionary conserved LIN54 subunit of LINC. We found that LIN54 is required for cell cycle progression....

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PMID: 19725879
DOI: 10.1111/j.1742-4658.2009.07261.x

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