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Article

Characterization of a functional ZBP-89 binding site that mediates Gata1 gene expression during hematopoietic development.

The Journal of biological chemistry - 30 Oct 2009

Ohneda Kinuko, Ohmori Shin'ya, Ishijima Yasushi, Nakano Mayu, Yamamoto Masayuki

Abstract excerpt

GATA-1 is a lineage-restricted transcription factor that plays essential roles in hematopoietic development. The Gata1 gene hematopoietic enhancer allowed Gata1 reporter expression in erythroid cells and megakaryocytes of transgenic mice. The Gata1 hematopoietic enhancer activity is strictly dependent on a GATA site located in the 5' region of the enhancer. However, the importance of the GC-rich region adjacent...

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Source

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Identifiers

PMID: 19723625
DOI: 10.1074/jbc.M109.026948
PMCID: PMC2781574

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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