Article
Prevalence of beta-2 adrenergic receptor (beta 2 AR) polymorphisms and its influence on a model used to assess endothelial function using pulse wave analysis (PWA).
Clinica chimica acta; international journal of clinical chemistry - 1 Nov 2009
Ibrahim Nik Nor Izah Nik, Rasool Aida Hanum Ghulam, Wong Abdul Rahim, Rahman Abdul Rashid Abdul
Abstract excerpt
BACKGROUND: Pulse wave analysis (PWA) combined with beta(2)-agonist challenge has recently been used to assess endothelial function. beta-2 adrenergic receptor (beta(2)AR) polymorphisms may affect response to beta(2)-agonist. We determined whether beta(2)AR polymorphisms influence endothelial response in our model using PWA and salbutamol. METHODS: 388 healthy Malay subjects (177 males, 211 females) were...
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