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Article

Association between arterial stiffness and variations in oestrogen-related genes.

Journal of human hypertension - 1 Oct 2009

Peter I, Kelley-Hedgepeth A, Huggins G S, Housman D E, Mendelsohn M E, Vita J A, Vasan R S, Levy D, Benjamin E J, Mitchell G F

Abstract excerpt

Increased arterial stiffness and wave reflection have been identified as cardiovascular disease risk factors. In light of significant sex differences and the moderate heritability of vascular function measures, we hypothesized that variation in the genes coding for oestrogen receptors alpha (ESR1) and beta (ESR2) and aromatase (CYP19A1) is associated with aortic stiffness and pressure wave reflection as measured...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19194457
DOI: 10.1038/jhh.2009.1
PMCID: PMC2746260

Genes

ESR1
ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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