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Article

Modulation of vascular smooth muscle cell phenotype by STAT-1 and STAT-3.

Atherosclerosis - 1 May 2014

Kirchmer Mayumi Namekata, Franco Anais, Albasanz-Puig Adaia, Murray Jacqueline, Yagi Mayumi, Gao Lu, Dong Zhao Ming, Wijelath Errol S

Abstract excerpt

OBJECTIVE: Smooth muscle cell (SMC) de-differentiation is a key step that leads to pathological narrowing of blood vessels. De-differentiation involves a reduction in the expression of the SMC contractile genes that are the hallmark of quiescent SMCs. While there is considerable evidence linking inflammation to vascular diseases, very little is known about the mechanisms by which inflammatory signals lead to SMC...

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Share to Cell Dedifferentiation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Muscle, Smooth, Vascular

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Identifiers

PMID: 24657387
DOI: 10.1016/j.atherosclerosis.2014.02.029

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