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Article

A role for galanin in human and experimental inflammatory demyelination.

Proceedings of the National Academy of Sciences of the United States of America - 8 Sept 2009

Wraith David C, Pope Robert, Butzkueven Helmut, Holder Heidi, Vanderplank Penny, Lowrey Pauline, Day Michael J, Gundlach Andrew L, Kilpatrick Trevor J, Scolding Neil, Wynick David

Abstract excerpt

The neuropeptide galanin is widely expressed by many differing subsets of neurons in the nervous system. There is a marked upregulation in the levels of the peptide in a variety of nerve injury models and in the basal forebrain of humans with Alzheimer's disease. Here we demonstrate that galanin expression is specifically and markedly upregulated in microglia both in multiple sclerosis (MS) lesions and shadow...

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Share to Analysis of Variance
Share to Encephalomyelitis, Autoimmune, Experimental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fluorescent Antibody Technique

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Source

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Identifiers

PMID: 19717462
DOI: 10.1073/pnas.0903360106
PMCID: PMC2732706

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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