Article
Generation and phenotypic characterization of a galanin overexpressing mouse.
Neuroscience - 1 Jan 2005
Holmberg K, Kuteeva E, Brumovsky P, Kahl U, Karlström H, Lucas G A, Rodriguez J, Westerblad H, Hilke S, Theodorsson E, Berge O-G, Lendahl U, Bartfai T, Hökfelt T
Abstract excerpt
In most parts of the peripheral nervous system galanin is expressed at very low levels. To further understand the functional role of galanin, a mouse overexpressing galanin under the platelet-derived growth factor-B was generated, and high levels of galanin expression were observed in several peripheral tissues and spinal cord. Thus, a large proportion of neurons in autonomic and sensory ganglia were...
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