Article
Decreased linezolid uptake in an in vitro-selected linezolid-resistant Staphylococcus epidermidis mutant.
The Journal of antimicrobial chemotherapy - 1 Nov 2009
Sierra J M, Ortega M, Tarragó C, Albet C, Vila J, Terencio J, Guglietta A
Abstract excerpt
OBJECTIVES: The aim of this study was to characterize the mechanism of resistance to linezolid in an in vitro-selected linezolid-resistant Staphylococcus epidermidis mutant. METHODS: A linezolid-resistant strain of S. epidermidis was selected by serial passages with increasing concentrations of linezolid. The MICs of linezolid, ciprofloxacin, tetracycline, rifampicin, vancomycin, gentamicin, tobramycin,...
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