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Article

Linezolid resistance in Staphylococcus aureus: characterization and stability of resistant phenotype.

The Journal of infectious diseases - 1 Dec 2002

Pillai Satish K, Sakoulas George, Wennersten Christine, Eliopoulos George M, Moellering Robert C, Ferraro Mary Jane, Gold Howard S

Abstract excerpt

Linezolid is an important therapeutic option for treatment of infections caused by glycopeptide- and beta-lactam-resistant gram-positive organisms. Linezolid resistance is caused by mutations within the domain V region of the 23S ribosomal RNA (rRNA) gene, which is present in multiple copies in most bacteria. Among clinical Staphylococcus aureus isolates, there has been only 1 reported case of linezolid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12447736
DOI: 10.1086/345368

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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