Article

Increased copy number of 23S ribosomal RNA gene with point mutation in MRSA associated with linezolid resistance in a patient treated with long-term linezolid

2022-11-03

Abstract excerpt

<h4>Background: </h4> Methicillin-resistant Staphylococcus aureus (MRSA) infection is one of the most difficult infections we have to treat. Linezolid is one of the effective treatment options for refractory MRSA infections. There are cases where we are forced to use long-term linezolid treatment for refractory MRSA infections. Objective To discuss the evolution of Linezolid resistance factors in clinical isolate...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a4eed28c-4b7d-51ac-81f2-43344143b8a2
DOI: 10.21203/rs.3.rs-2217318/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Increased copy number of 23S ribosomal RNA gene with point mutation in MRSA associated with linezolid resistance in a patient treated with long-term linezolidDOI 10.21203/rs.3.rs-2217318/v1Read

The emerging problem of linezolid-resistant <i>Staphylococcus</i>Semantic proximity Read

Endemic linezolid-resistant Staphylococcus epidermidis in a critical care unit.Semantic proximity Read

Detection of linezolid resistance cfr gene among MRSA isolatesSemantic proximity Read

Linezolid resistance in Staphylococcus aureus: characterization and stability of resistant phenotype.Semantic proximity Read

Phenotypic and genotypic characterization of linezolid resistance and the effect of antibiotic combinations on methicillin-resistant Staphylococcus aureus clinical isolates.Semantic proximity Read

Resistance to linezolid is mediated by the cfr gene in the first report of an outbreak of linezolid-resistant Staphylococcus aureus.Semantic proximity Read

Parallel Evolution of Linezolid Resistant <i>Staphylococcus aureus</i> in Patients with Cystic FibrosisSemantic proximity Read

Linezolid update: stable in vitro activity following more than a decade of clinical use and summary of associated resistance mechanisms.Semantic proximity Read

Emergence of methicillin-resistant coagulase-negative staphylococci resistant to linezolid with rRNA gene C2190T and G2603T mutations.Semantic proximity Read

Parallel evolution of linezolid-resistant Staphylococcus aureus in patients with cystic fibrosisSemantic proximity Read

Five-Year Summary of In Vitro Activity and Resistance Mechanisms of Linezolid against Clinically Important Gram-Positive Cocci in the United States from the LEADER Surveillance Program (2011 to 2015)Semantic proximity Read

Persistence of rRNA operon mutated copies and rapid re-emergence of linezolid resistance in Staphylococcus aureus.Semantic proximity Read