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Article

Resistance to linezolid: characterization of mutations in rRNA and comparison of their occurrences in vancomycin-resistant enterococci.

Antimicrobial agents and chemotherapy - 1 Jul 2001

Prystowsky J, Siddiqui F, Chosay J, Shinabarger D L, Millichap J, Peterson L R, Noskin G A

Abstract excerpt

To assess the potential for emergence of resistance during the use of linezolid, we tested 10 clinical isolates of vancomycin-resistant enterococci (VRE) (four Enterococcus faecalis, five Enterococcus faecium, and one Enterococcus gallinarum) as well as a vancomycin-susceptible control (ATCC 29212) strain of E. faecalis. The enterococci were exposed to doubling dilutions of linezolid for 12 passes. After the...

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Identifiers

PMID: 11408243
DOI: 10.1128/AAC.45.7.2154-2156.2001
PMCID: PMC90620

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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