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Resistance to linezolid is mediated by the cfr gene in the first report of an outbreak of linezolid-resistant Staphylococcus aureus.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Mar 2010

Morales Gracia, Picazo Juan J, Baos Elvira, Candel Francisco J, Arribi Ana, Peláez Beatriz, Andrade Raquel, de la Torre María-Angeles, Fereres José, Sánchez-García Miguel

Abstract excerpt

BACKGROUND: From April through June 2008, we identified 12 patients in the intensive care unit and 3 patients on other wards infected with methicillin-resistant Staphylococcus aureus that was also resistant to linezolid. We investigated the mechanism of resistance--point mutations in domain V of 23S ribosomal RNA (rRNA) or presence of the cfr gene--involved in the outbreak. METHODS: Strains for the study were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20144045
DOI: 10.1086/650574

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