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Article

Functional consequences of mutations in the Drosophila histamine receptor HCLB.

Journal of insect physiology - 1 Jan 2010

Yusein Shazie, Wolstenholme Adrian, Semenov Eugene

Abstract excerpt

The gene hclB encodes a histamine-gated chloride channel subunit in Drosophila melanogaster. Mutations in hclB lead to defects in the visual system and altered sensitivity to the action of ivermectin. To investigate whether this member of the Cys-loop receptors is common across the Insecta, we analysed the genomes of seven other insect species (Diptera, Hymenoptera, Coleoptera) and revealed orthologues of hclB in...

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Identifiers

PMID: 19716373
DOI: 10.1016/j.jinsphys.2009.08.016
PMCID: PMC2805722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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