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Article

The target of Drosophila photoreceptor synaptic transmission is a histamine-gated chloride channel encoded by ort (hclA).

The Journal of biological chemistry - 1 Nov 2002

Gengs Chaoxian, Leung Hung-Tat, Skingsley David R, Iovchev Mladen I, Yin Zhan, Semenov Eugene P, Burg Martin G, Hardie Roger C, Pak William L

Abstract excerpt

By screening Drosophila mutants that are potentially defective in synaptic transmission between photoreceptors and their target laminar neurons, L1/L2, (lack of electroretinogram on/off transients), we identified ort as a candidate gene encoding a histamine receptor subunit on L1/L2. We provide evidence that the ort gene corresponds to CG7411 (referred to as hclA), identified in the Drosophila genome data base,...

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Identifiers

PMID: 12196539
DOI: 10.1074/jbc.M207133200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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