Article
Phylogenetic shadowing of a histamine-gated chloride channel involved in insect vision.
Insect biochemistry and molecular biology - 1 Jan 2006
Iovchev Mladen, Boutanaev Alexander, Ivanov Ivaylo, Wolstenholme Adrian, Nurminsky Dmitry, Semenov Eugene
Abstract excerpt
A recently identified gene, hclA (synonym: ort), codes for an ionotrophic histamine receptor subunit in Drosophila melanogaster, and known hclA mutations lead to defects in the visual system, neurologic disorders and changed responsiveness to neurotoxins. To investigate whether this novel class of receptors is common across the Insecta, we analysed the genomes of 15 other insect species (Diptera, Hymenoptera,...
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