Article
Ipl1/Aurora B kinase coordinates synaptonemal complex disassembly with cell cycle progression and crossover formation in budding yeast meiosis.
Genes & development - 15 Sept 2009
Jordan Philip, Copsey Alice, Newnham Louise, Kolar Elizabeth, Lichten Michael, Hoffmann Eva
Abstract excerpt
Several protein kinases collaborate to orchestrate and integrate cellular and chromosomal events at the G2/M transition in both mitotic and meiotic cells. During the G2/M transition in meiosis, this includes the completion of crossover recombination, spindle formation, and synaptonemal complex (SC) breakdown. We identified Ipl1/Aurora B kinase as the main regulator of SC disassembly. Mutants lacking Ipl1 or its...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
