Article
Zip4/Spo22 is required for class I CO formation but not for synapsis completion in Arabidopsis thaliana.
PLoS genetics - 25 May 2007
Chelysheva Liudmila, Gendrot Ghislaine, Vezon Daniel, Doutriaux Marie-Pascale, Mercier Raphaël, Grelon Mathilde
Abstract excerpt
In budding yeast meiosis, the formation of class I interference-sensitive crossovers requires the ZMM proteins. These ZMM proteins are essential in forming a mature synaptonemal complex, and a subset of these (Zip2, Zip3, and Zip4) has been proposed to compose the core of synapsis initiation complexes (SICs). Zip4/Spo22 functions with Zip2 to promote polymerization of Zip1 along chromosomes, making it a crucial...
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