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Article

Tam1, a telomere-associated meiotic protein, functions in chromosome synapsis and crossover interference.

Genes & development - 15 Jul 1997

Chua P R, Roeder G S

Abstract excerpt

The TAM1 gene of Saccharomyces cerevisiae is expressed specifically during meiosis and encodes a protein that localizes to the ends of meiotic chromosomes. In a tam1 null mutant, there is an increase in the frequency of chromosomes that fail to recombine and an associated increase in homolog nondisjunction at meiosis I. The tam1 mutant also displays an increased frequency of precocious separation of sister...

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Identifiers

PMID: 9242487
DOI: 10.1101/gad.11.14.1786

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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