Article
Genotyping for NOD2 genetic variants and crohn disease: a metaanalysis.
Clinical chemistry - 1 Nov 2009
Yazdanyar Shiva, Weischer Maren, Nordestgaard Børge G
Abstract excerpt
BACKGROUND: Arg702Trp, Gly908Arg, and Leu1007fsinsC variants of the NOD2 gene (nucleotide-binding oligomerization domain containing 2; alias, CARD15) influence the risk of Crohn disease. METHODS: We conducted a systematic review to examine whether Arg702Trp, Gly908Arg, and Leu1007fsinsC are equally important risk factors for Crohn disease. In addition, we used studies for which combined information from all...
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